Nathan Boone. The date of the photo is unknown. [State Historical Society of Missouri, R. L. Hosman Collection (P0925)]

Nathan Boone, the youngest child of Daniel and Rebecca Bryan Boone, was born on March 2, 1781, at Boone’s…

A 1911 State Highway Department map of the Boone’s Lick Road and Santa Fe Trail. [State Historical Society of Missouri Map Collection, 850 M691h 1911]

The Boone’s Lick Road was the first major conduit to the trans-Mississippi West after the 

Henry Marie Brackenridge. [State Archives of Florida, Florida Memory]

A lawyer, author, diplomat, and journalist in the early Federal and Jacksonian eras, Henry…

Robert Campbell. [Missouri Historical Society, St. Louis, Photographs and Prints Collection, N38642]

Robert Campbell’s lengthy life bridged the transition from fur trade to modern capitalistic…

Auguste Chouteau. [Missouri Historical Society, St. Louis, 1869-001-0001]

In the early history of St. Louis and its trans-­Mississippi hinterlands, Auguste Chouteau…

Jean Pierre Chouteau Sr. [Missouri Historical Society, St. Louis, Photographs and Prints Collection, N22207]

Jean Pierre Chouteau, known as Pierre, was a pioneer settler in St. Louis and the territory that was to…

Francois M. Guyol de Guiran created this portrait of Marie Therese Bourgeois Chouteau, the “founding mother” of St. Louis, in 1810. [Missouri Historical Society, St. Louis, MHS Objects Collection, 1950-084-0002]

Marie Thérèse Bourgeois Chouteau was born in New Orleans on January 14, 1733, but she was…

Pierre Chouteau Jr. [Missouri Historical Society, St. Louis, Photographs and Prints Collection, 1922-024-0001]

Pierre Chouteau Jr., scion of the powerful early St. Louis family and the most influential…

Note of Jacques Clamorgan agreeing to pay skins worth $153 to Pierre Chouteau on July 19, 1807. [Missouri Historical Society, St. Louis, Clamorgan Family Papers, A0288-00017]

Jacques Phillippe Clamorgan arrived on the Missouri frontier in the early 1780s and spent the rest of his…

Franscisco Cruzat served two terms as lieutenant governor of Upper Louisiana in New Spain. [Alcée Fortier, A History of Louisiana, 1904]

Francisco Cruzat, the only Spanish lieutenant governor of Upper Louisiana to occupy that…